Qinsi Zheng

Company: Orum Therapeutics

Job title: Principal Scientist

Seminars:

PROTAb Platform: An Innovative Universal Linker for DACs With CereblonBased Degraders 1:30 pm

An introduction into PROTAb – Orum’s traceless linker technology for Degrader-Antibody Conjugate (DAC). It improves the effectiveness of cereblon-based degraders by enabling stable conjugation to therapeutic antibodies Understanding the technology used, including a Mannich base self-immolative spacer to form stable DAC, releasing the active degrader tracelessly upon intracellular triggering Reviewing the versatility and compatibility with…Read more

day: Day One