This workshop explores the latest approaches to tuning linker performance and conjugation chemistry for ADCs, degraders, peptides, and oligonucleotide conjugates — helping teams engineer reliable, reproducible constructs that translate successfully to the clinic.

• Exploring linker stability, cleavability, and compatibility with degraders, oligos, and peptides
• Addressing conjugation challenges with non-traditional payloads and formats (e.g. enzymatic vs. chemical conjugation)
• Case studies on linker selection for tissue-specific delivery and overcoming off-target toxicity
• Identify future directions in cleavable, condition-responsive, and bioorthogonal linker systems