Explore the Agenda
8:00 am Check in & Registration
Workshop A
9:00 am Designing Holistically: Aligning Targeting Scaffold & Payload Strategy in Novel Conjugates
This workshop explores how targeting format, payload, and linker choices interact to shape efficacy, safety, and clinical strategy, by bringing together a unique audience across the targeting format and payload landscape to understand where different modalities can complement one another for success.
- Understand how targeting format (monoclonal, bispecific, antibody fragment, peptide) influences payload selection and mechanism of action
- Evaluate whether monoclonal antibodies remain optimal for emerging payloads such as degraders and oligonucleotides
- Compare design trade-offs between bispecific targeting and payload potency, stability, and exposure
- Explore compatibility challenges and linker considerations when combining new payload types with novel scaffolds
- Develop an integrated design framework that connects discovery, chemistry, and translational perspectives
12:00 pm Networking Lunch
Workshop B
1:00 pm Designing Linker Technologies & Conjugation Approaches that Support the Unique Properties of Novel Payloads & Targeting Formats
This workshop explores the latest approaches to tuning linker performance and conjugation chemistry for ADCs, degraders, peptides, and oligonucleotide conjugates — helping teams engineer reliable, reproducible constructs that translate successfully to the clinic.
- Exploring linker stability, cleavability, and compatibility with degraders, oligos, and peptides
- Addressing conjugation challenges with non-traditional payloads and formats (e.g. enzymatic vs. chemical conjugation)
- Case studies on linker selection for tissue-specific delivery and overcoming off-target toxicity
- Identify future directions in cleavable, condition-responsive, and bioorthogonal linker systems